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Avi A capsule in treating plaque-type psoriasis ef

Avermectin A capsule (trade name Chinese side hopes) is the second generation of retinoic acid-type drugs, since 1997 proved to be pustular and erythrodermic psoriasis is effective,eco yoga mat, but a separate treatment of plaque-type silver crumbs of inforpvc mation and rare diseases. Our hospital in October 2005 -2,007 years in March were 29 patients with plaque psoriasis treated patients achieved good effect, are reported below.
1 clinical data of 1.1 inclusion criteria can be selected male and female patients, aged 18 to 65 years of age; condition in a stable period; patients agree to use Chinese side hopes; women of *****bearing age are not pregnant or planning to become pregnant during treatment is not necessary, and urine pregnancy may be ruled out . 1.2 Exclusion criteria in the top four weeks had received systemic anti-psoriasis therapy or PUVA treatment; pregnant and lactating women and 2 a desire within pouch belt *****-bearing women; right Avermectin A or other retinoic acid-type drugs allergy; serious liver and kidney dysfunction, hyperlipidemia persons, disorder, or excessive Vitamin A Vitamin A and its metabolites against allergies. 1.3 General inforyoga mation were treated in 29 patients with psoriasis, of which 1 case because of adverse reactions to withdraw midway. Actually completed in 28 cases, male 18 cases, female 10 cases; aged 19 ~ 65 (41.26 ± 8.64) years of age; course of disease 3 months ~ 10a (3.47 ± 4.69) a. 1.4 Treatment for 3 d pre-treatment screening period, giving Chinese side hopes (Chongqing, China Pharmaceutical Co., Ltd. to help produce) 20mg / d orally, patients selected if tolerated. Named after the Chinese side hopes to give 30mg / d, fat side can dose 40mg / d; while giving the vitamin B, vitamin C and vitamin E orally to reduce adverse reactions such as cheilitis; with a single cream, cream, or cortex Hepudiod steroid cream for external use. Zhu Huanzhe low-fat diet, 3 ~ 4 weeks after the Chinese side hopes bear fruit reduction to 20 mg / d to maintain, with a total course of 12 to 16 weeks. In the treatment of 4,8,12 and 16 weeks respectively, followed up by doctors to the lesion area, respectively, erythema, infiltration, scaling ratings. Treatment by a doctor and patient overall assessment ratings, respectively. 1.5 Evaluation of approach to 1.5.1 Psoriasis Area marking 0 = no lesions, 1 = lesion area of 10%, 2 = lesion area of 10% ~ 29%, 3 = lesion area of 30% ~ 49% , 4 = lesion area of 50% ~ 69%, 5 = lesion area of 70% ~ 89%, 6 = lesion area of 90%. 1.5.2 Psoriasis symptoms (erythema, infiltration and scaling) marking 0 = no skin involvement, 1 = lesions symptoms of mild, 2 = moderate degree of symptoms of skin lesions, 3 = lesion extent of the symptoms was severe. 1.5.3 psoriasis severity scoring the severity of psoriasis lesions of area sub-total score = × (scaling rate score erythema infiltration rate). 1.5.4 Evaluation of methods based more: the end of treatment to reduce psoriasis severity Total 90%; markedly: pouch belt end of treatment of psoriasis severity Total reduced by 60% to 89%; effective: the end of treatment of psoriasis Total extent of reduction of 21% to 59%; invalid: After treatment of psoriasis severity total score reduced by 20%. 1.5.5 doctors and patients assessment of the overall effectiveness of the treatment 0 = no change or symptoms get worse, 1 = improved, 2 = marked improvement, 3 = cured. 2 results of 28 cases of psoriasis patients after treatment using the Chinese side hopes the base more in 6 cases, 9 cases markedly effective, effective in 11 cases, 2 cases, markedly effective rate 54%, efficiency 93%. A variety of clinical manifestations and integral change and fade, treatment before and after the doctor and patient overall efficacy of treatment evaluation of points changes, see Table l, Table 2 (omitted). Of which 1 patient because of the lips chapped, unbearable, abnormal blood lipid tests increased two times more than to withdraw from this experiment. 3 to discuss the clinical evidence, Avi A co-UVB or PUVA treatment of plaque-type psoriasis is effective, but how the single-drug treatment, at present little inforyoga mation on coverage. I use Avi A capsule 28 cases of plaque-type psoriasis, effective rate is 54% effective rate was 93%, skin lesions of psoriasis symptoms: skin lesions of area, erythema, infiltration, scaling points marked improvement, serious Total reduced the extent of 74%. Doctors and patients assessment of overall efficacy of treatment the total score increased by 38% and 39%. The above indicators compared with those before treatment there was significant difference (P were 0.05). Avermectin A capsules on adverse reactions, 29 patients in one cases of severe cheilitis can not tolerate the withdrawal of most patients after oral administration of a variety of vitamins, with the lipstick can be put up. Tests of liver function and blood lipids, abnormal shall be given Lipitor Liver tablets and after discontinuation laboratory indicators back to normal. Other rare adverse reactions are itching, dry eyes, fatigue, anorexia, appetite changes, hair loss, gastrointestinal reactions not affect people's life and work, withdrawal recovery. Minge Wei A capsule that has a good tolerance. In short, for plaque psoriasis, Avi A capsule can be used as a single system, medication, adverse reactions is small, easily accepted by patients in clinical practice are worth promoting. Recommend reading articles:

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